Cancer and Stem Cell Research and Application Center (MUKKAM)

Publications

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Ulugol RK, Tuylu H, Aktas RG.  Evaluation of In-Vitro Effects of Collagen Supplements on Liver Cancer  . 4th Internatıonal Medical Student Congress of Bucharest. The Book of Full Text, ISSN 2601- 1743. page 42 (2020)  


Akbulut Z,Kavaklı AO, Koroglu Karagoz A, Maras H, Aktas RG. Temperature and Carbondioxide Changes Related To Type I Collagen Presence On Hepatocellular Carcinoma Cells.  Research and Science Today, 20(2):193-204 (2020)


Akbulut Z, Koser F, Kayali DG, Maras H, Aktas RG. The Effects of Type I Collagen on The Cell Skeletal Organization of Liver Cancer Cells in The Proliferation Differentiation Phase. 5.Uluslararası Tıp ve Sağlık  Bilimleri Araştırmaları Kongresi (UTSAK), Online- 12-13 Aralık 2020 

Kayali DG, Çavdaroğlu S, Korhan BE, Aktas RG. Effects Of Hıgh Dose Insulin On Cell Proliferation And Alpha Feto Proteın Expressıon In Human Liver Cancer Cell Line Models. 3rd Internatıonal Bıltek Conference. The Book of Full Text, 122-133 (2020)


Kayali DG, Korhan BE, Şen A, Çavdaroğlu S, Aktas RG. Investigation of Anticancer Activities of Various Extracts of Tanacetum Argenteum Subsp. Argenteum Plant on Human Liver Cancer Cell Line. 3rd Internatıonal Bıltek Conference 23-24 (2020)


Ozunal ZG, Cakil YD, Tekin S, Saglam E, Aktas RG. Metoclopramide increased cell proliferation in HepG2 cell line and sorafenib attenuated the effect. The Annals of Medical Research. 27(4): 1188-92 (2020)


Ozunal ZG, Cakil YD, Saglam E, Aktas RG. Effect of Escitalopram Alone or Combination with Sorafenib on HepG2 Hepatocellular Cell Line. Research and Science Today. 1(19): 201-210 (2020) 


Ozunal ZG, Cakil YD, Isan H, Saglam E, Aktas RG. Sertralin in combination with sorafenib: A promising pharmacotherapy to target both depressive disorders and hepatocellular cancer. Biologica Futura. 70(4):341-348 (2019)


Ayyildiz M, Aktas RG, Basdoğan C.Effect of solution and post-mortem time on mechanical and histological properties of liver during cold preservation. Biorheology. 51(1): 47-70 (2014).


Yarpuzlu B, Ayyildiz M, Tok OE, Aktas RG, Basdogan C. Correlation between the Mechanical and Histological Properties of Liver Tissue. J Mech Behav Biomed Mater. 29:403-16 (2014).


Ozunal ZG, Cakil YD, Isan H, Saglam E, Aktas RG. Effects of Fluvoxamine and Its combination with Sorafenib on the Proliferation of Hepatocellular Cancer HepG2 Cells. 32nd ECNP Congress, Abstract Book, P757, S509, 2019.


Saglam E, Ozunal ZG, Cakil YD, Isan H, Aktas RG. Effects of Fluoxetine and Its Combination with Sorafenib on the Proliferation of Hepatocellular Cancer HepG2 Cells. 32nd ECNP Congress, Abstract Book, P751, S504, 2019.


Aktas RG, Cakil Y, Akbulut Z, Isan H, Karagoz A, Kayali D, Sitar E, Kisakol B, Baysan M. Multi-Dimensional Data Visualization Related to Hepatocellular Carcinoma: Another Step to Precision Medicine for Diagnosis and Prognosis of Liver Cancer. BioIT World Conference & Expo, Proceedings, 2019.  


Akbulut Z, Cakil YD, Isan H, Karagoz A, Kayalı GD, Sitar ME, Aktas RG. The Effect of 3D- Microenvironment and Level of Collagen Type I on Immunomodulatory Genes, Wnt signalling Pathway and Alpha-fetoprotein Expression in Hepatocellular Carcinoma Cells:  A Genomic, Morphological and Functional Comparative Study. International Molecular Medicine Symposium, Istanbul, May 16-18, 2019.


Akbulut Z, Isan H, Cakil YD, Sitar ME, Aktas RG. The Relationship Between Microenvironment, Immunomodulatory Genes, Wnt Signalling Pathway and Alpha-fetoprotein Expression in Hepatocellular Carcinoma Cells: A Genomic, Morphologic and Functional Comparative Study. 2nd International Health Sciences Congress, Abstract Book, 03394, 2018.


Isan H, Akbulut Z, Cakil YD, Sitar ME, Aktas RG. The Effects of Type I Collagen on the Properties of Liver Cancer Cells Related to Adhesion, Differentiation and Carcinogenity:  A Comparative Fine Structural, Functional and Genomic Study 2nd International Health Sciences Congress, Abstract Book, 03392, 2018.


Akbulut Z, Isan H, Cakil YD, Aktas RG. Collagen Type I Changes Expression of Apoptosis Related Genes Both at Proliferation and Differentiation Stages of Hepatocellular Carcinoma Cells. 10th International Heinrich F. C.  Behr-Symposium on Stem Cells and Cancer. Abstract Book, 87, Heidelberg, Germany, 2018.


Isan H, Akbulut Z, Cakil YD, Aktas RG. The Relationship Between Cancer Stem Cells, Epithelial Mesenchymal Transition and Microenvironment Containing Type I Collagen During Proliferation and Differentiation Stages of Hepatocellular Carcinoma Cells. 10th International Heinrich F. C.  Behr-Symposium on Stem Cells and Cancer. Abstract Book, 86, 2018.


Tatar G, Isan H, Sitar ME, Aktas RG. Morphological, Physiological and Biochemical Effects of Passage Numbers on Long Term Culture of Differentiating HepG2 Cells. 10th International Heinrich F. C.  Behr-Symposium on Stem Cells and Cancer. Abstract Book, 88, 2018.


Tuyluoglu H, Toksoz A, Isan H, Aktas RG. Changes at the Subcellular Localization and Dynamics of Anti-Apoptotic p53, p57, and BCL 2 Under the Effect of Collagen. International Summit of Innovation in Medicine. Abstract Book, 106, 2018.


Tok OE, Aktas RG. Serial passaging effects the carcinogenicity, stemness and spheroid formation of HEPG2 cells, a hepatocellular carcinoma cell line. 13th Multinational Congress on Microscopy, Abstract Book, 401-402, 2017.


Caliskan EB, Isan H, Camas A, Aktas RG. Time Dependent Changes at the Mitochondria of Hepatocellular Carcinoma Cells During Hypothermia. 15th International Congress of Histochemistry and Cytochemistry. Abstract Book. 317, 2017.


Aktas RG, Erinc M, İsan H, Uzun S. Low dose- Long Term Dimethyl sulfoxide (DMSO) reduces carcinogenity and changes some morphological and biochemical properties of HepG2 cells. The Annual Meeting of the American Society for Cell Biology, Meeting Abstracts, P1921, Mol Biol Cell, 2016.


Aktas RG, İsan H, Caliskan EB, Tok OE, Aydin MS, Kaya OT. Dose dependent effects of Dimethyl Sulfoxide on the Mitochondria of Hepatocellular Carcinoma Cells. The Annual Meeting of the American Society for Cell Biology, Meeting Abstracts, P1921, Mol Biol Cell, 2016.


Guner DC, Sirolu C, Yildiz A, Gul CC, Isan H, Aktas RG.  Evaluation of cytotoxic effects of dimethylsulfoxide (DMSO) on Hepg2 cells during thawing period. The Annual Meeting of the American Society for Cell Biology, Meeting Abstracts, Mol Biol Cell, 2015.


Aktas RG and Tok OE. Localization of embryonic stem cell markers (Oct4, Nanog, Sox2, SSEA-4, TRA-1) in tumour spheroids of hepatocellular carcinoma cell line after confluency in long-term cell cultures. 2nd International Congress on Stem Cell and Cellular Therapies, October 15 -18 2015, Antalya, Turkey.


Aktas RG, Erdin S, Apa DD, Isan H. Effects of confluency on morphological and functional properties of HepG2 cells, a hepatocellular carcinoma cell line. EACR Sponsored 3ed Anticancer Agent Development Congress, abstract Book, PP-098, 155, 2015.


Yavas SE, Turk E, Aktas RG. Cancer Stem Cells. SUBAT 1st International Student Congress, Abstracts, Page 144-145, March 20-22 2015.


Aktas RG. Can a Cancer Cell Turn Into a Normal Cell? JOP. J Pancreas (Online) 2014 Sep 28; 15(5):539, 2014.


Aktas RG, Tok OE. Expression Patterns of F-Actin and Nanog, an embryonic stem cell marker, in monolayer and spheroid culture of human liver carcinoma cell line. The American Society for Cell Biology and International Federation of Cell Biology  Meeting Abstracts, Mol Biol  Cell, 2014.


Aktas RG, Isan H, Aras D, Balikcilar M, Bayar U. Changes at the Expression Levels of Alpha-fetoprotein, Inhibin, Chromogranin, Estrogen Receptor and Progesterone Receptor According to the Different Localization in Full Term Human Normal Placenta. Turkish Journal of Reproductive Medicine and Surgery, 2(3):93-100, 2018.


Isan H, Tufekci K, Goklu ME, Aktas RG. The Effects of Mechanic Stress, Due to Centrifuge After Freezing–Thawing Process, on In Vitro Culture of Liver Cancer Cells. Maltepe Medical Journal, 8 (3): 001-005, 2016.


Aktas RG, Demiralay E, Yıidiz S.  Diversity of Histochemical and Electron Microscopic Results in Primary Lung Cancer: A Retrospective Study of 21 Cases. Maltepe Medical Journal,8 (3): 006-011, 2016.


Isan H, Tombus O, Goklu ME, Tufekci K, Aktas RG.  The Effect of Different Cell Culture Surfaces on the Growth Proliferation Rate and Morphology of the Hepatocellular Carcinoma Cells.  Maltepe Medical Journal, 8 (3): 012-017, 2016.


Isan H, Tombus AC, Dogru HO, Sanlı G, Aktas RG. The Relationship Between the Hepatocellular Carcinoma Cells and the Cell Culture Duration: A Quantitative Comparative Confocal Microscopic Study. Maltepe Medical Journal,8 (3): 018-023, 2016.


Tatar G, Sengül E, Isan H, Aktas RG.The Effects of Passage Number on Spheroid Formation of Liver Cells. Maltepe Medical Journal, 8 (3): 024-028, 2016.


Aktas RG, Altunkaynak ME, Tunalı G, Arat N, Sofuoglu K, Cogendez E, Kutlu T, Devranoglu B, Ankaralı H. Effects of Laser Zona Thinning On Pregnancy Rates In Patients With Implantation Failure. Maltepe Medical Journal, 6 (2): 1-7, 2014.


Oner C, Gozdersi Y, Isan H, Aktas RG, Colak E. Does Vitamin D have therapeutic effects for liver cancer? The Preliminary Data. 7th Multidisiciplinary Cancer Research & 1st Basic Oncology Congress, October 11,14, 2018, Izmir, Turkey, 2018.


Camas A, Kosan D, Isan H, Aktas RG. Live Cell Imaging of Hepatocellular Carcinoma Cells Under Hypothermia. 6th National Medical Students Congress, Trabzon, Turkey, 2018.


Aras D, Balikcilar M, Isan H, Bayar U, Aktas RG. Expression of Alpha Fetoprotein, Inhibin, Chromogranin, Estrogen and Progesterone in Term Placentae Changes According to The Location of the Cell. 2nd National Student Congress: Reproductive Biology and Infertility. Canakkale, Turkey, 2017


Isan H and Aktas RG. The Effects of Different Vitrification Techniques on Expression of Embryonic Stem Cell Markers: Nanog, Oct, Sox2 and SSEA4. 4th Clinical Embryology Congress, Bodrum, Turkey, 2017.  


Güner DC, Isan H, Şirolu C, Aktaş RG. Apopitosis and Liver Cancer Cells 1st PRATET Congress, November 6-8, Canakkale, Turkey, 2015.


Isan H, Göklü ME, Tüfekçi K, Misyağci M, Aktaş RG. The Effects of Different Culture Surfaces on Growth, Proliferation and Morphology of Hepatocellular Carcinoma Cells. 1st PRATET Congress, Canakkale, Turkey, 2015.


Tüfekçi K, Göklü ME, Qipa E, Isan H, Aktaş RG.  The Effects of Mechanical Stress by Sentrifuge After Freezing and Thawing Process on Hepatocellular Carcinoma Cells.  1st PRATET National Medical Students Congress, Canakkale, Turkey, 2015.


Hazır K, Güzelce E, Tok OE, Esrefolu M, Aktas RG. Light and Confocal Microscopic Visualsation of “Nanog”, a protein which plays a key role on embriyonal stem cells, in prostate and liver cancer cells. Stem Cell Student Symposium, Abstract Book, Page: 72, 2014.


Garip A, Uzak E, Tok OE, Esrefoglu M, Aktas RG. Apoptotic Changes on Kidney After Low Term Low Dose of Cyclosporin Application. III. Cerrahpasa Science Days, Abstracts Book, Page:52, 2014.