Research

Investigation of Intracellular Oxidative Stress in Hepatocellular Carcinoma Cell Line (HepG2) in Classical Culture and Type I Collagen-Coated Culture Media. Student: Mertcan Atay, Dr. Zeynep Akbulut, Prof. Dr. Ranan Gülhan Aktaş (2020-Present)

Histological and Biochemical Investigation of the Effects of Fructose on Human Liver Cancer Cell Line. Student: Ayşe Latifoğlu, Researcher: Damla Kayalı, M.Sc., Prof. Dr. Ranan Gülhan Aktaş (2020-Present)

Effects of Type 1 Collagen in Two and Three-Dimensional Culture Media on Oleic Acid-Induced Lipid Accumulation in Liver Cancer Cells. Student: Öykü Çıtakoğlu, Researcher: Damla Kayalı, M.Sc., Prof. Dr. Ranan Gülhan Aktaş (2020-Present)

Effects of High Insulin Dosage on Cell Proliferation and Alpha-Fetoprotein Expression in Human Liver Cancer Cell Line Models. Prof. Dr. Ranan Gülhan Aktaş, Researcher: Damla Kayalı, Sude Çavdaroğlu (2019-Present)

Investigation of Anticancer Activities of Various Extracts of Tanacetum argenteum subsp. argenteum on Liver and Breast Cancer Cell Lines. Prof. Dr. Ranan Gülhan Aktaş, Researcher: Damla Kayalı, Betül Eda Korhan (2019-Present)

The Effect of Borax on the Proliferation of Hepatocellular Carcinoma Cells in Different Culture Media. Prof. Dr. Ranan Gülhan Aktaş, Researcher: Hatice İsan, Ahmet Enis Alaca (2019-Present)

Effects of Type I Collagen on Cytoskeletal Organization of Liver Cancer Cells during Proliferation and Differentiation Phases. Prof. Dr. Ranan Gülhan Aktaş, Researcher: Dr. Zeynep Akbulut, Faruk Köser (2019-Present)

In Vitro Investigation of the Morphological and Carcinogenic Properties of Type I and Type III Collagen Used as Dietary Supplements on Liver Cancer Cells. Prof. Dr. Ranan Gülhan Aktaş, Researcher: Reyhan Kahveci Ulugöl, Havva Tüylüoğlu (2019-Present)

Investigation of the Effects of Inhibiting PIWI-Interacting RNA Regions on the Malignancy of Metastatic Breast Cancer Cells. Asst. Prof. Çağrı Öner (2019-Present)

Determination of the Relationship Between PIWI-Interacting RNAs, Estrogen Receptor, and Cellular Mechanisms in Breast Cancer. Asst. Prof. Çağrı Öner (2019-Present)

Identification of Sorafenib-Resistant Liver Cancer Cells: Cancer Stem Cell Characterization. Asst. Prof. Yaprak Dönmez Çakıl, Prof. Dr. Ranan Gülhan Aktaş, Dr. Zeynep Özünal (2019-Present)

Pharmacological Treatment Approaches for Acute Kidney Injury in Naturally Aged and Experimental Rodents. Asst. Prof. Feride Sinem Akgün, Assoc. Prof. Mustafa Erinç Sitar, Asst. Prof. Zeynep Güneş Özünal, Asst. Prof. Mehmet Şerif Aydın, Student: Hazal Karadağ (2019-Present)

Relationship Between Liver Cancer Cells and Carnosic Acid. Prof. Dr. Ranan Gülhan Aktaş, Researcher: Hatice İsan, Dilara Kolsan (2018-2019)

Effect of Microenvironmental Temperature and Ambient Carbon Dioxide Changes on Cell Death in Hepatocellular Carcinoma Cell Culture Models. Prof. Dr. Ranan Gülhan Aktaş, Dr. Zeynep Akbulut, Ayşe Özge Kavaklı (2018-2019)

Changes Induced by 4-OH Coumarin in the Characteristic Properties of Hepatocellular Carcinoma Cells. Asst. Prof. Çağrı Öner, Dilara Soyergin, Ahmet Özyurt (2018-2019)

In Vitro Evaluation of the Effects of Metoclopramide on Proliferation in HepG2 Liver Cancer Cell Line. Prof. Dr. Ranan Gülhan Aktaş, Dr. Zeynep Güneş Özünal, Sena Tekin (2018-2019)

Effect of Active Vitamin D3 on the Characteristic Properties of HepG2 Liver Cancer Cells. Asst. Prof. Çağrı Öner (2018-2019)

Investigation of the Effect of High Glucose Concentration on Spindle Assembly Checkpoint Activity. Asst. Prof. Pınar Buket Demirel (2018-2019)

Effects of Sertraline Alone and in Combination with Sorafenib on HepG2 Hepatocellular Cancer Cell Line. Esra Sağlam, Asst. Prof. Yaprak Dönmez Çakıl, Prof. Dr. Ranan Gülhan Aktaş, Dr. Zeynep Özünal (2018-2019)

Effects of Fluoxetine and Fluvoxamine Alone or in Combination with Sorafenib on HepG2 Hepatocellular Cells. Esra Sağlam, Asst. Prof. Yaprak Dönmez Çakıl, Prof. Dr. Ranan Gülhan Aktaş, Dr. Zeynep Özünal (2018-2019)

Effect of Escitalopram Alone or in Combination with Sorafenib on HepG2 Hepatocellular Cell Line. Prof. Dr. Ranan Gülhan Aktaş, Asst. Prof. Yaprak Dönmez Çakıl, Dr. Zeynep Özünal, Esra Sağlam (2018-2019)

Effect of Paroxetine Alone or in Combination with Sorafenib on HepG2 Hepatocellular Cell Line. Prof. Dr. Ranan Gülhan Aktaş, Asst. Prof. Yaprak Dönmez Çakıl, Dr. Zeynep Özünal, Hatice İsan (2018-2019)

Determination of Toxicological Effects of Different Quantum Dots on Zebrafish (Danio rerio, Hamilton, 1822). Prof. Dr. Nagihan Gülsoy, Res. Asst. Nur Kaluç (2018-2020)

The Role of Programmed Cell Death in Floral Diversity: Model System Gynodioecious Helianthus annuus L. (Sunflower). Özlem Aytürk, Özal Mutlu, Tuncay Uludağ, Cenk Önal (2018-2020)

Comparative Evaluation of Morphological, Functional, and Genetic Changes, Carcinogenic Properties, and Presence of Cancer Stem Cell Markers in Differentiating Liver Cancer Cells: Can a New Data Analysis System Be Created to Determine Liver Cancer Prognosis? Prof. Dr. Ranan Gülhan Aktaş, Asst. Prof. Mustafa Erinç Sitar, Assoc. Prof. Tuğba Bağcı Önder, Asst. Prof. Mehmet Baysan, Post-doctoral Fellow: Zeynep Akbulut (2017-2019)

Morphological and Functional Characterization and Investigation of Differentiation Potential of Liver Cancer Stem Cells Isolated from HepG2 Cells. Prof. Dr. Ranan Gülhan Aktaş (2017-2018)

Effect of Microenvironmental Temperature and Ambient Carbon Dioxide Changes on Cell Death in Hepatocellular Carcinoma Cell Culture Models. Prof. Dr. Ranan Gülhan Aktaş, Dr. Zeynep Akbulut, Ayşe Özge Kavaklı (2017-2019)

Spindle Assembly Checkpoint in Chromosome Abnormalities: Evaluation of Slx5 as a Chemotherapeutic Target in Saccharomyces cerevisiae Model. Asst. Prof. Pınar Buket Demirel, Elif Ergin Çavuşoğlu (2016-2019)

Biochemical Effects of Low-Dose Dimethyl Sulfoxide on Hepatocellular Carcinoma Cells. Prof. Dr. Ranan Gülhan Aktaş, Asst. Prof. Erinç Sitar (2016-2018)

Can Differentiating Liver Cancer Cells Serve as a Better Model for Artificial Liver Studies? Prof. Dr. Ranan Gülhan Aktaş (2016-2017)

Investigation of Programmed Cell Death in Reproductive Organs of the Dioecious Plant Zea mays using Molecular Methods. Asst. Prof. Özlem Aytürk (2016-2018)

Comparative Evaluation of Liver Cancer Stem Cells Isolated from HepG2 Cells in terms of Differentiation Potential, Morphological and Functional Properties. Prof. Dr. Ranan Gülhan Aktaş, Asst. Prof. Erinç Sitar, Hatice İsan, Prof. Dr. Feriha Ercan (2016-2018)

Determination of the Roles of Epigenetic Modification of Adipokines and MicroRNAs in Preventing Breast Tumor Development through Intermittent Caloric Restriction in MMTV-TGF-Alpha Mice. Asst. Prof. Pınar Buket Demirel (2014-2017)

In Vitro Production of Polyploid Plants in Sunflower (Helianthus annuus L.). Asst. Prof. Özlem Aytürk (2015-2017)

Study of Programmed Cell Death in Flowers of Dioecious Spinacia oleracea (Chenopodiaceae). Asst. Prof. Özlem Aytürk (2015-2017)

Biochemical and Morphological Changes in Hepatocellular Carcinoma Cells Depending on the Culture Process. Prof. Dr. Ranan Gülhan Aktaş, Asst. Prof. Erinç Sitar (2014-2017)

Time-Dependent Change in the Response of Liver Cancer Cells to Hypothermic Conditions. Prof. Dr. Ranan Gülhan Aktaş (2015-2016)

Effects of Controlled Slow Freezing and Vitrification Techniques on the Expression of Embryonic Stem Cell Markers Nanog, Oct4, Sox2, and SSEA4 in Embryos and Embryo-Derived Stem Cells. Hatice İsan, Prof. Dr. Ranan Gülhan Aktaş, Dr. Ali Cihan Taşkın (2015-2017)

Comparative Morphological and Biochemical Evaluation of the Effects of Varying Doses of Retinoic Acid Application on Liver Cancer Cell Differentiation. Prof. Dr. Ranan Gülhan Aktaş (2015-2017)

Can Differentiating Liver Cells Serve as a Better Model for Artificial Liver Studies? Prof. Dr. Ranan Gülhan Aktaş and Prof. Dr. Feriha Ercan (2014-2016)